Hepatic Silicone Granulomas Secondary to Ruptured Breast Implants: A Report of Two Cases

Figure 5

(a) Liver biopsy from Case 2 shows a classic silicone granuloma with multinucleated giant cells (arrows) containing clear vacuoles of varying sizes portraying a “swiss cheese-like” appearance. H&E stain, 20x. (b) A portal tract from Case 2 is filled with silicone granulomas and demonstrates periportal ductular reaction (arrows) with associated neutrophilic inflammation indicative of bile duct obstruction. H&E stain, 10x.

(a)

(b)