Development of Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 21 Years after Achieving a Sustained Virological Response to Interferon Therapy

<div>Histological findings of the liver biopsy specimen. (a) Moderate lymphocytic infiltrates in the portal areas of hepatic lobules with slightly piecemeal necrosis (hematoxylin and eosin staining; magnification, ×40). (b) Fibrous expansion of portal areas with occasional portal-to-portal bridging (= F3 fibrosis) (Masson’s trichrome staining; magnification, ×40).</div>

Case Reports in Hepatology

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Figure 1

Figure 1: Development of Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 21 Years after Achieving a Sustained Virological Response to Interferon Therapy 

Figure 1 | Development of Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 21 Years after Achieving a Sustained Virological Response to Interferon Therapy 