Case Report

Development of Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 21 Years after Achieving a Sustained Virological Response to Interferon Therapy

Table 1

Laboratory findings on admission.

Variable

White blood cells (/μL)4390
Red blood cells (104/μL)396
Hematocrit (%)39.1
Hemoglobin (g/dL)13.0
Platelets (104/μL)14.1
PT-INR0.96
PT (%)107.5
Total protein (g/dL)6.3
Albumin (g/dL)4.1
C-reactive protein (mg/dL)0.05
BUN (mg/dL)16
Creatinine (mg/dL)0.88
T-chol (mg/dL)173
Glucose (mg/dL)92
HbA1c (%)5.8
Total bilirubin (mg/dL)0.7
AST (IU/L)17
ALT (IU/L)12
ALP (IU/L)207
GGT (IU/L)17
AFP (ng/mL)19
PIVKA-II (mAU/mL)60
CEA (ng/mL)1.3
CA19-9 (U/mL)3
HCV AbPositive
HCV-RNANegative
HBsAgNegative
HBsAbNegative
HBcAbNegative
FIB-4 index2.68

PT, prothrombin time; PT-INR, prothrombin time-international normalized ratio; BUN, blood urea nitrogen; T-chol, total cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; AFP, alpha-fetoprotein; PIVKA-II, protein induced by vitamin K absence or antagonist-II; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; HCV Ab, hepatitis C virus antibody; HBsAg, hepatitis B surface antigen; HBsAb, hepatitis B surface antibody; HBcAb, anti-hepatitis B core antibody; FIB-4 index, fibrosis-4 index.