Case Report

ANCA-Associated Intrahepatic Duct Injury Associated with Levamisole-Adulterated Cocaine

Table 1

Pertinent laboratory values.

Laboratory testValues at presentationValues at dischargeReference values

Total bilirubin13.02.6(0.2–1.0 mg/dL)
Direct bilirubin11.1(0.0–0.2 mg/dL
Alkaline phosphatase520233(45–117 units/L)
AST196196(15–37 units/L)
ALT235235(16–61 units/L)
PT10.3(9.0–12.5)
INR1.0(1.0–1.5)
Anti-MPO (p-ANCA)>100(0.0–9.0)
p-ANCA1 : 80(<1 : 20)
Antiproteinase 3 (c-ANCA)8.7(0.0–3.5)
c-ANCA<1 : 20(<1 : 20)
Anti-α-SMA14(0–19)
Anticentromere7.3(0.0–0.9)

AST: aspartate aminotransferase; ALT: alanine aminotransferase; PT: prothrombin time; INR: international normalized ratio; MPO: myeloperoxidase; ANCA: antineutrophil cytoplasmic antibodies; SMA: smooth muscle actin. By enzyme immunoassay. By indirect immunofluorescence assay.