Treatment-Resistant Hepatitis C Viral Infection: A Case Report and Literature Review

Table 1

The evolution of pertinent lab results: pretreatment, during treatment, and posttreatment.

Labs	Dates
	Pretreatment							During treatment				Posttreatment
	Apr-19	Aug-19	Dec-19	Jan-20	Jul-20	Sep-20	Jan-21	Feb-21	Mar-21	Apr-21	May-21	Jun-21	Aug-21	Sep-21
AST, U/L	107	47	72	87	108	94	93	109	81	49	44	70	49	51
ALT, U/L	73	27	44	51	64	55	48	66	50	36	31	43	28	30
ALP, U/L	53	53	57	78	81	80	112	99	83	77	83	84	96	108
Total bilirubin, mg/dL	1.5	1	1.0	1.1	1.9	1.5	1.2	1.2	2.3	2.6	2.8	1	1.3	1.3
PT/INR	1.2	1.2	NT	NT	NT	1.2	1.1	1.2	1.2	1.1	1.1	1.2	1.2	1.1
Platelets, 10^3/μL	115	197	67	54	78	100	106	108	103	107	117	105	92	107
Albumin, g/dL	3.6	4.2	3.5	3.3	3.4	3.6	3.3	3.6	3.6	3.5	3.6	3.8	3.6	3.5
Creatinine, mg/dL	0.8	1.4	0.7	0.6	0.9	0.8	0.8	1.0	0.9	0.8	0.8	0.9	1.2	0.9
eGFR, mL/min/1.73 m^2	>90	62	52	>90	85	92	95	85	85	85	93	83	61	80
Sodium, mmol/L	136	137	136	135	135	134	134	135	136	135	138	135	136	136
HCV-RNA quant (IU)	338,000	NT	6,510,00	NT	1,550,000	NT	NT	NT	ND	ND	ND	ND	ND	ND

NT, not tested; ND, not detected.