Autoimmune Lymphoproliferative Syndrome and Epstein-Barr Virus-Associated Lymphoma: An Adjunctive Diagnostic Role for Monitoring EBV Viremia?
Figure 1
EBV viremia and EBV+ lymphoma in ALPS. A 33-year-old male with ALPS-Ia developed asymptomatic worsening lymphadenopathy (Right axillary lymph node in July 2011 (a) and June 2012 (b)), with progressively increasing EBV viral load (VL). He was found to have a composite EBV+ lymphoma. (c) Monitoring of whole blood EBV VL demonstrates an increasing viremia with concomitant identification of lymphoma and improvement in viremia with (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone; R-CHOP) chemotherapy.
