Successful Management of Insulin Allergy and Autoimmune Polyendocrine Syndrome Type 4 with Desensitization Therapy and Glucocorticoid Treatment: A Case Report and Review of the Literature

Table 4

Desensitization protocol using Glargine insulin.

Day	Number of	Accumulated dose (IU)	Total dosage per day (IU)	Local reaction (cm)
1	1	0,001	0,001	1
1	2	0,01	0,011	0
1	3	0,1	0,111	1,5
1	4	1	1,111	0
1	5	2	3,111	0
2	6	0,1	0,1	1
2	7	1	1,1	0
2	8	2	3,1	0
2	9	3	6,1	0
3	10	2	2	0
3	11	3	5	0
3	12	4	9	0
4	13	12	12	0
5	14	12	12	0
5	15°	12	24	0

  between injections: 20 minutes.
°Administrated almost simultaneously with dosage number 14, in a different corporal region.
Diameter of the flare.