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Case Reports in Immunology
Volume 2015, Article ID 591438, 2 pages
Case Report

A Case Report of Allergic Contact Dermatitis due to Mandragora Radix

Department of Dermatology, Yıldırım Beyazıt Training and Research Hospital, 06120 Ankara, Turkey

Received 22 June 2015; Accepted 26 July 2015

Academic Editor: Cassian Sitaru

Copyright © 2015 Sevim Baysak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An 82-year-old male presented with rash, burning, and itching on his knees that had started 4 days after the local application of Mandragora Radix sap for 3 consecutive days. A dermatological examination revealed erythematous, edematous, and scaly plaque lesions on the patient’s knees. An open application test with M. Radix was performed, and the patient was diagnosed with allergic contact dermatitis due to M. Radix. Mandragora species, which belong to the Solanaceae family, have sedative, aphrodisiac, emetic, analgesic, and anesthetic properties. To the best of our knowledge, only one case of M. Radix-induced allergic contact dermatitis has been previously reported.