Table 2: Reports of metastatic melanoma in the bone marrow, results of systematic review.

AuthorsAgePresenting symptomsPrimaryTreatmentOutcome

Battle and Stasney [5]60Weight lossOcularSupportiveDeath, 2 months
Rubinstein [6]47Cord compressionOccultThiouracilDeath, 2 months
Franklin et al. [7]67Back painSkinSupportiveDeath.
Franklin et al. [7]18FatigueSkinNot reportedUnknown
Brown et al. [8]66 Malaise, weight lossOcularSupportiveDeath, months
Basile et al. [9]63Abnormal CBCOccultChemotherapyDeath, 6 months
Villarrubia et al. [10]57PetechiaeSkinNot reportedUnknown
Invernizzi and Pecci [11]34FeverSkinNot reportedUnknown
Chim and Trendell Smith [12]67Red eyeOcularNot reportedUnknown
Basu et al. [13]74FatigueAnusNot reportedUnknown
Basu et al. [13]35Cord compressionTonsilNot reportedUnknown
Batsis and Barry [14]75Altered mental statusSkinSupportiveDeath, 3 weeks
Uesawa et al. [15]67Back painSkinNot reportedUnknown
Jain et al. [16]22EpistaxisOccultChemotherapyUnknown
Bhandari et al. [17]62Fever, joint painOcularSupportiveUnknown
Downing et al. [18]49Low back painSkinNot reportedUnknown
Hsiao and Chen [19]76Low back painOcularSupportiveDeath, 2 months
Suzuki et al. [20]77Bleeding, DICOccultSupportiveDeath, 1 week
Bertolotti et al. [21]55DyspneaSkinSupportiveDeath, days
Velasco-Rodríguez et al. [22]75EpistaxisSkinChemotherapyDeath, 2 months
Serrier and Lesesve [23]60Dyspnea, back painSkinSupportiveDeath, days
Ferla et al. [24]70Fever, back painSkinSupportiveDeath, 3 months
Mirfazaelian et al. [25]61Abdominal painOccultNot reportedUnknown
Kalodimos et al. [26]81PancytopeniaSkinChemotherapyUnknown
Volejnikova et al. [27]5Back pain, feverSkinIpilimumabDeath, 4 months
Kassam and Shah [28]79Weight lossOccultSupportiveDeath, 2 weeks
Fukumoto et al. [29]26Back painSkinNivolumabDeath, 3 months
Rosner et al. [30]64Fatigue, FeverSkinPembrolizumabGood response
Baniak et al. [31]13Pleural effusionPleuralNot reportedUnknown