Effective Immunotherapy in Bone Marrow Metastatic Melanoma Presenting with Disseminated Intravascular Coagulopathy

Table 2

Reports of metastatic melanoma in the bone marrow, results of systematic review.

Authors	Age	Presenting symptoms	Primary	Treatment	Outcome
Battle and Stasney [5]	60	Weight loss	Ocular	Supportive	Death, 2 months
Rubinstein [6]	47	Cord compression	Occult	Thiouracil	Death, 2 months
Franklin et al. [7]	67	Back pain	Skin	Supportive	Death.
Franklin et al. [7]	18	Fatigue	Skin	Not reported	Unknown
Brown et al. [8]	66	Malaise, weight loss	Ocular	Supportive	Death, months
Basile et al. [9]	63	Abnormal CBC	Occult	Chemotherapy	Death, 6 months
Villarrubia et al. [10]	57	Petechiae	Skin	Not reported	Unknown
Invernizzi and Pecci [11]	34	Fever	Skin	Not reported	Unknown
Chim and Trendell Smith [12]	67	Red eye	Ocular	Not reported	Unknown
Basu et al. [13]	74	Fatigue	Anus	Not reported	Unknown
Basu et al. [13]	35	Cord compression	Tonsil	Not reported	Unknown
Batsis and Barry [14]	75	Altered mental status	Skin	Supportive	Death, 3 weeks
Uesawa et al. [15]	67	Back pain	Skin	Not reported	Unknown
Jain et al. [16]	22	Epistaxis	Occult	Chemotherapy	Unknown
Bhandari et al. [17]	62	Fever, joint pain	Ocular	Supportive	Unknown
Downing et al. [18]	49	Low back pain	Skin	Not reported	Unknown
Hsiao and Chen [19]	76	Low back pain	Ocular	Supportive	Death, 2 months
Suzuki et al. [20]	77	Bleeding, DIC	Occult	Supportive	Death, 1 week
Bertolotti et al. [21]	55	Dyspnea	Skin	Supportive	Death, days
Velasco-Rodríguez et al. [22]	75	Epistaxis	Skin	Chemotherapy	Death, 2 months
Serrier and Lesesve [23]	60	Dyspnea, back pain	Skin	Supportive	Death, days
Ferla et al. [24]	70	Fever, back pain	Skin	Supportive	Death, 3 months
Mirfazaelian et al. [25]	61	Abdominal pain	Occult	Not reported	Unknown
Kalodimos et al. [26]	81	Pancytopenia	Skin	Chemotherapy	Unknown
Volejnikova et al. [27]	5	Back pain, fever	Skin	Ipilimumab	Death, 4 months
Kassam and Shah [28]	79	Weight loss	Occult	Supportive	Death, 2 weeks
Fukumoto et al. [29]	26	Back pain	Skin	Nivolumab	Death, 3 months
Rosner et al. [30]	64	Fatigue, Fever	Skin	Pembrolizumab	Good response
Baniak et al. [31]	13	Pleural effusion	Pleural	Not reported	Unknown