Case Report

Mendelian Susceptibility to Mycobacterial Disease: The First Case of a Diagnosed Adult Patient in the Czech Republic

Table 2

Time sequence of clinical manifestations.

Year of catchmentLocalizationPathogen

1981Inguinal and cervical lymph nodesM. kansasii
1992LungsWrongly diagnosed as sarcoidosis
1993Lymph nodes, Th-7, 8, 9, 11, 12, L1, 2, 5 left femur, maxilla, mandibulaM. kansasii
1995Centre in the distal part of the left femurM. avium intracellulare
M. gordonae
1997Granuloma in the right faceM. lentiflavum
1998Left patella
Distal part of the femur on the right
Granuloma in the right face
M. lentiflavum
M. kansasii
2001Granuloma of the nasal septumM. avium intracellulare
2002Left kneeM. flavescens
2004SputumM. lentiflavum
2007Granuloma/nasal septumM. lentiflavum
2009Granuloma/nasal septumM. lentiflavum
2013Granuloma/nasal septumM. avium
2014TH 8, 11, L1, L5M. avium
2016Granuloma of the nasal septumM. lentiflavum
2017Colliquating granuloma in the nasal septumM. avium intracellulare
2018Granuloma of the nasal septum
Colliquating granuloma in the right face
M. avium
Start therapy rhIFN-γ
2020Surgery of the nasal septum
Granuloma of the right face healed
Microbiological investigation is negative