Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager
Table 2
Summary of the patient’s immunological profile.
Parameter
Normal range
Baseline
17 years old
Blood hemoglobin (g/dL)
12–15.4
13
13.5
Blood platelets (G/L)
150–400
219
357
Blood leukocytes (mm3)
3900–11.000
10.400
10.200
Blood neutrophils (%)
40–75
68.6
59.8
Blood lymphocytes (%)
19–48
23.7
30.2
Monocytes (%)
3.4–9
5.3
6.97
Eosinophils (%)
0–7
1.9
2.12
Basophils (%)
0–1.5
0
0.8
IgA (mg/dl)
26.50 (NR: 60–220)
72.40 (NR: 70–400)
IgG (mg/dl)
717 (NR: 600–1300)
784 (NR: 700–1600)
IgM, (mg/dl)
50.80 (NR: 40–160)
61.60 (NR: 40–230)
IgE (IU/ml)
61.30 (NR: <52)
54.20 (NR: <378)
IgG1 (mg/dl)
633 (NR: 561–1100)
556 (NR: 405–1011)
IgG2 (mg/dl)
89.80 (NR: 86–355)
164 (NR: 169–426)
IgG3 (mg/dl)
53 (NR: 31–100)
27 (NR: 11–85)
IgG4 (mg/dl)
15.60 (NR: 20–117)
42.30 (NR: 3–201)
CD2 T cells (%)
75.9–84.9
75.3
75.9
CD3+ T cells (%)
55–78
69
71.1
CD3+/CD4+ (%)
27–53
52
49.1
CD3+/CD8+ (%)
19–34
12.5
15.9
CD3−/CD16+CD56+ NK (%)
4–26
18.9
4.6
CD19+ B cells (%)
10–31
10.2
20.1
CD23 (%)
N/D
13.4
CD4+/CD8+ ratio
0.9–2.6
4.2
3.08
CD3+/γδ
18.5
N/D
CD3+/αβ
76.1
N/D
DHR1,2,3 (%)
97.3
97.5
Baseline, first investigation of the patient. NR, normal ranges, DHR1,2,3, Dihydrorhodamine test. The IgA and IgG4 values are in bold to suggest that they are below the normal range.
