Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
Figure 1
Radiographic and pathologic appearance of adenovirus infection of the liver. (Patient 1: Panels (a)–(d)) CT of the abdomen (a) showed two large hypodense lesions in the liver. On post-mortem examination, the liver had multiple large areas of necrosis ((b) and (c)). Immunohistochemistry of thin sections of the liver confirmed the presence of adenovirus (d). Subsequent testing revealed adenovirus, serotype 5. (Patient 2: Panels (e)–(h)) CT of the abdomen showed multiple small hypodense lesions in the liver (e). The liver had multiple small areas of necrosis ((f) and (g)). Immunohistochemistry of the liver confirmed the presence of adenovirus (h). Subsequent testing revealed adenovirus, serotype 2.
