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Case Reports in Infectious Diseases
Volume 2013, Article ID 293823, 3 pages
Case Report

Syphilis, Hepatitis, and Pancreatitis: Is the Uncommon Becoming Common in the HIV+ Patient?

Department of Internal Medicine, MedStar Harbor Hospital, 3001 South Hanover Street, Baltimore, MD 21225, USA

Received 18 September 2013; Accepted 3 November 2013

Academic Editors: J.-F. Faucher, M. Ghate, C. L. Gibert, A. Marangoni, A. C. Sena, T. Shibata, and P. O. Sumba

Copyright © 2013 B. A. da Silva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Coinfection with human immunodeficiency virus (HIV) and syphilis has been occurring at increasing rates, with the greatest increases being seen among men who have sex with men. Secondary syphilis rarely presents with liver disease, and the diagnosis may be overlooked in favor of more common causes of liver injury in this setting, such as viral hepatitis, antiretroviral therapy, alcohol use, and opportunistic infections. Case Presentation. We describe a 43-year-old patient with HIV who presented with symptoms suggesting acute pancreatitis. Investigation led to a diagnosis of hepatitis and pancreatitis, both attributed to syphilis. Conclusion. Syphilis should be included as part of the initial diagnosis among patients with HIV presenting with abnormal liver and pancreatic enzymes.