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Case Reports in Infectious Diseases
Volume 2014, Article ID 352047, 4 pages
Case Report

A Case of Ocular Syphilis in a 36-Year-Old HIV-Positive Male

1University of Colorado School of Medicine, AO1, Room 8505, 12631 East 17th Avenue, Mail Stop B166, Aurora, CO 80045, USA
2Department of Internal Medicine, University of Colorado School of Medicine, 12631 East 17th Avenue, B177, Aurora, CO 80045, USA
3Department of Medicine and Division of Infectious Diseases, Denver Health Medical Center, 660 Bannock Street, Denver, CO 80204, USA
4Division of Infectious Diseases, University of Colorado, Anschutz Medical Campus, Research Complex 2, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO 80045, USA

Received 21 February 2014; Accepted 17 July 2014; Published 11 August 2014

Academic Editor: Pere Domingo

Copyright © 2014 Amy Nguyen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The incidence of syphilis in the United States has increased markedly over the last decade, particularly among men who have sex with men (MSM). Although uncommon, ocular involvement is a potentially devastating clinical manifestation of syphilis. Human immunodeficiency virus (HIV) infection appears to increase the risk of ocular syphilis. Because of the lack of pathognomonic features for ocular syphilis and its ability to occur in both immunocompetent and immunosuppressed individuals, prompt diagnosis requires a high index of suspicion. Ocular syphilis should therefore be considered in MSM and HIV-infected patients presenting with unexplained visual complaints. Herein, we present a case of ocular syphilis in a patient with newly diagnosed HIV.