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Case Reports in Infectious Diseases
Volume 2014, Article ID 865909, 4 pages
http://dx.doi.org/10.1155/2014/865909
Case Report

Acute Myeloid Leukemia Presenting with Pulmonary Tuberculosis

1Pulmonary Medicine, Hamad General Hospital, P.O. Box 3050, Doha, Qatar
2Department of Medicine, Hamad General Hospital, Doha, Qatar

Received 30 January 2014; Revised 30 April 2014; Accepted 11 May 2014; Published 28 May 2014

Academic Editor: Lawrence Yamuah

Copyright © 2014 Merlin Thomas and Mushtak AlGherbawe. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report the case of a 58-year-old immunocompetent man presenting with fever, cough, anorexia, weight loss, and cervical lymphadenopathy. Blood investigations revealed severe neutropenia with monocytosis. Chest imaging showed bilateral reticular infiltrates with mediastinal widening. Bronchoalveolar lavage culture and molecular test were positive for Mycobacterium tuberculosis and treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol was started. Although pulmonary tuberculosis could explain this clinical presentation we suspected associated blood dyscrasias in view of significant monocytosis and mild splenomegaly. Bone marrow aspiration revealed acute myeloid leukemia. Thereafter the patient received induction chemotherapy and continued antituberculous treatment. After first induction of chemotherapy patient was in remission and successfully completed 6 months antituberculosis therapy without any complications. To our knowledge there has been no such case reported from the State of Qatar to date.