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Case Reports in Infectious Diseases
Volume 2015, Article ID 175810, 3 pages
Case Report

Differences in Method-Specific Vancomycin MICs and Induced Daptomycin Resistance in an Infective Endocarditis Patient

1Department of Pharmacy, Kern Medical Center, Bakersfield, CA 93306, USA
2Department of Medicine, Kern Medical Center, Bakersfield, CA 93306, USA

Received 27 February 2015; Accepted 27 April 2015

Academic Editor: Paola Di Carlo

Copyright © 2015 David Benjamin Lash et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Methicillin-resistant Staphylococcus aureus (MRSA) is a common nosocomial infection that has a high burden of morbidity and mortality. Vancomycin is the often-used antibiotic of choice when MRSA is suspected as a causative infectious agent. Recent studies have called into question the reliability of vancomycin as empiric therapy, especially in instances of bacteremia. The isolate’s minimum inhibitory concentration (MIC), the source of infection, modality of susceptibility testing, and antibiotic resistance are all issues that should be taken into consideration when formulating a care plan for a patient. We present a case that illustrates some of these issues clinicians are facing.