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Reference/year | Age | Infection | Risk factor | Treatment | Clinical outcome |
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Dooley et al., 1990 [8] | 57 y | Hansenula fabianii prostatitis | CLL, recurrent urethral self-manipulation | 10-, 14-, and 28-d courses with ketoconazole, followed by AMB, duration NR. | Relapse off azole therapy. With AMB, the patient had lasting relief without recurrence of infection. |
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Valenza et al., 2006 [9] | 46 y | Candida fabianii bloodstream, lung | Antibacterial therapy, enterocolitis | FLU for 15 d, followed by caspofungin daily for 7 d. | Disseminated intravascular coagulation, ischemic bowel, and persistent shock. Death at ICU, day 68. |
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Bhally et al., 2006 [11] | 5 weeks | Pichia fabianii BSI | Prematurity, antibacterial therapy, and enterocolitis | AMB for 22 d. Vascular catheter removal on d 2. | Resolution of infection without sequelae at long-term follow-up. |
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Hamal et al., 2008 [10] | 40 y | Pichia fabianii endocarditis | Congenital combined aortic incompetence of the mitral valve, recent craniectomy | FLU for 48 d, then VOR for 21 d, and then AMB for 35 d. Cardiac surgery after 28 d on AMB. | Recurrent stroke prior to cardiac surgery. Following surgery and AMB, no further evidence of infection. |
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Grenouillet et al., 2010 [12] | 11 d | Pichia fabianii skin lesion, BSI, and empyema | Prematurity, antibacterial therapy, and premature rupture of membranes | FLU (duration NR) and then AMB and FC for 10 d (until death). | Gastrointestinal and tracheal hemorrhage. Oliguric renal failure. Death on 41 d of life. |
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Gabriel et al., 2012 [14] | 53 y | Lindnera fabianii BSI | Antibacterial therapy, mesenteric ischemia | CAS for 19 d, followed by FLU for 91 d, and bowel resection. | Discharge from hospital on d 110. |
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Yun et al., 2013 [15] | 47 y | Lindnera fabianii BSI | Antibacterial therapy, transplantation, steroids, and neutropenia | AMB (dose NR) for 8 d, followed by CAS for 14 d. | Multiorgan failure, shock, and death. |
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Wu et al., 2013 [13] | 3 weeks | Pichia fabianii BSI | Low birth weight, broad spectrum antibiotics | FLU for 18 d. | Resolution of infection with discharge from hospital. |
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Mlinarić-Missoni et al., 2015 [16] | 3.5 y/F | C. fabianii BSI | Leukemia, neutropenia, and antibacterial therapy | FLU for 5 d and then AMB for 14 d. | Clearance of fungemia after 3 d. Resolution of infection with discharge from hospital. |
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Mlinarić-Missoni et al., 2015 [16] | 2 months/M | C. fabianii UTI | Hydronephrosis, surgery, and antibacterial therapy | FLU for 27 d, urinary catheter removal. | Clearance of culture after 11 d. Discharge from hospital. |
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Mlinarić-Missoni et al., 2015 [16] | Neonate/F | C. fabianii UTI | Gastroschisis, surgery, mechanical ventilation, parenteral nutrition, and antibacterial therapy | FLU for 27 d, urinary catheter removal, and CVC removal. | Clearance of culture after 5 d. Discharge from hospital. |
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Mlinarić-Missoni et al., 2015 [16] | Neonate/M | C. fabianii UTI | Hydronephrosis, surgery, parenteral nutrition, and antibacterial therapy | FLU for 30 d and then CAS for 10 d. | Clearance of culture after 10 d. Discharge from hospital. |
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Mlinarić-Missoni et al., 2015 [16] | Neonate/F | C. fabianii BSI | Intestinal atresia, surgery, parenteral nutrition, and antibacterial therapy | FLU for 15 days, CVC removal. | Clearance of culture after 7 d. Discharge from hospital. |
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Mlinarić-Missoni et al., 2015 [16] | Neonate/F | C. fabianii BSI | Pulmonary cyst, 740 g weight, antibacterial therapy, mechanical ventilation, and parenteral nutrition | FLU for 2 d and then CAS for 21 d. | Clearance of culture after 7 d. Discharge from hospital. |
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