An Adverse Drug Reaction to Trimethoprim-Sulfamethoxazole Revealing Primary HIV: A Case Report and Literature Review

Table 1

Results of the patient’s infectious work-up demonstrating a significantly elevated viral load and slightly depressed CD4 cell count. The remainder of the evaluation was negative, showing no signs of other active infectious processes. Ab, antibody; Ag, antigen; DFA, direct florescent antibody test; CMV, cytomegalovirus; HAV, hepatitis A virus; HBV, hepatitis B virus; HCV, hepatitis C virus; HSV, herpes simplex virus; IgG, immunoglobulin G; IgM, immunoglobulin M; RPR, rapid plasma reagin; VZV, varicella zoster virus.

Lab	Result	Reference range
HIV-1 RNA viral load	9,645,190	Not detected
CD4+	407	441–2156 cell/µL
CD4+/CD8+	0.62	1.0–3.6
HSV Ag by DFA (penis)	(−)	(−)
HSV Ag by DFA (buccal)	(−)	(−)
VZV Ag by DFA	(−)	(−)
HSV 1 Ab IgG	0.91	0.0–0.90
HSV 1 Ab IgM	<1 : 10	<1 : 10
HSV 2 Ab IgG	3.28	0.0–0.90
HSV 2 Ab IgM	<1 : 10	<1 : 10
CMV	(−)	(−)
RPR	(−)	(−)
HAV Ab	(−)	(−)
HBV surface Ag	(−)	(−)
Anti-HBV surface Ab	(+)	(−)
Anti-HBV core Ab IgG	(+)	(−)
Anti-HBV core Ab IgM	(−)	(−)
HCV Ab	(−)	(−)
Parvovirus B19 Ab IgG	4.7	0.0–0.8
Parvovirus B19 Ab IgM	0.3	0.0–0.8