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Case Reports in Infectious Diseases
Volume 2015, Article ID 759341, 3 pages
Case Report

Miliary Tuberculosis Induced Acute Liver Failure

1Department of Hematology, Van Training and Research Hospital, 65300 Van, Turkey
2Department of Internal Medicine, Marmara University Hospital, Istanbul, Turkey
3Department of Infectious Diseases, Marmara University Hospital, Istanbul, Turkey
4Department of Gastroenterology, Marmara University Hospital, Istanbul, Turkey
5Department of Hematology, Marmara University Hospital, Istanbul, Turkey

Received 21 April 2015; Accepted 21 June 2015

Academic Editor: Pere Domingo

Copyright © 2015 Tayfur Toptas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hepatobiliary tuberculosis is uncommon even in endemic countries. It is associated with a high mortality and is even diagnosed early in the disease course. Acute liver failure (ALF) caused by tuberculosis bacilli has been reported in only a few reports. All previous cases have been diagnosed by postmortem examination. Time to antituberculosis treatment is very critical. In case of suggestive findings on clinical and radiologic examination, antituberculosis treatment should be initiated immediately. Drug use can be a challenge in patients with ALF. However, as long as the other possible causes of ALF can be excluded and hepatotoxic drugs were avoided during the early course of treatment, such a highly fatal presentation of tuberculosis can be treated safely. Here, we report a case of acute liver failure as a presentation of miliary tuberculosis. He was treated successfully with antituberculosis treatment.