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Case Reports in Infectious Diseases
Volume 2016, Article ID 1082160, 3 pages
Case Report

Edwardsiella tarda Endocarditis Confirmed by Indium-111 White Blood Cell Scan: An Unusual Pathogen and Diagnostic Modality

Division of Cardiovascular Disease, Department of Medicine, University of Tennessee Medical Center Knoxville, Graduate School of Medicine, 1924 Alcoa Hwy, Knoxville, TN 37920, USA

Received 26 October 2015; Revised 16 December 2015; Accepted 22 December 2015

Academic Editor: Sinésio Talhari

Copyright © 2016 Kayleigh M. Litton and Bret A. Rogers. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Edwardsiella tarda is a freshwater marine member of the family Enterobacteriaceae which often colonizes fish, lizards, snakes, and turtles but is an infrequent human pathogen. Indium-111- (111In-) labeled white blood cell (WBC) scintigraphy is an imaging modality which has a wide range of reported sensitivity and specificity (from 60 to 100% and from 68 to 92%, resp.) for diagnosing acute and chronic infection. We describe a case of suspected E. tarda prosthetic aortic valve and mitral valve endocarditis with probable vegetations and new mitral regurgitation on transthoracic and transesophageal echocardiograms which was supported with the use of 111In-labeled WBC scintigraphy.