Case Report
Acute and Fatal Isoniazid-Induced Hepatotoxicity: A Case Report and Review of the Literature
Table 1
Laboratory data upon admission.
| | Laboratory test | Result | Normal range |
| | Biochemistry | | | | Total bilirubin | 11.4 mg/dL | <1 mg/dL | | Direct bilirubin | 9.9 mg/dL | 0–0.2 mg/dL | | Indirect bilirubin | 1.5 mg/dL | 0-1 mg/dL | | -GTP | 202 U/L | <40 U/L | | ALP | 316 U/L | 35–105 U/L | | AST (SGOT) | 2099 U/L | <33 U/L | | ALT (SGPT) | 1096 U/L | <34 U/L | | CRP | 1.54 mg/dL | <0.5 mg/dL | | Amylase | 115 U/L | 28–100 U/L | | Lipase | 97 U/L | 13–60 U/L | | Total proteins | 5.2 g/dL | 6.6–8.7 g/dL | | Albumin | 2.9 g/dL | 3.5–5.2 g/dL |
| | Hematology | | | | WBC | 4.8 × 103/µL | 5.2–12.4 × 103/µL | | RBC | 4.5 × 106/µL | 4.2–5.4 × 106/µL | | Hb | 13.7 g/dL | 12–16 g/dL | | PLT | 237 × 103/µL | 130–400 × 103/µL |
| | Coagulation | | | | INR | 1.58 | 1–1.3 |
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Abnormal value.
-GTP: Gamma-Glutamyl Transpeptidase; ALP: Alkaline Phosphatase; AST: Aspartate Aminotransferase; SGOT: Serum Glutamic Oxaloacetic Transaminase; ALT: Alanine Aminotransferase; SGPT: Serum Glutamic Pyruvic Transaminase; CRP: C-Reactive Protein; WBC: White Blood Cell Count; RBC: Red Blood Cell; Hb: Hemoglobin; PLT: Platelet; INR: International Normalized Ratio.
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