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Case Reports in Infectious Diseases
Volume 2017, Article ID 1402320, 4 pages
https://doi.org/10.1155/2017/1402320
Case Report

Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device

1Infection Management Unit, The Prince Charles Hospital, Brisbane, QLD 4032, Australia
2School of Medicine, University of Queensland, Brisbane, QLD, Australia
3Department of Pharmacy, The Prince Charles Hospital, Brisbane, QLD 4032, Australia

Correspondence should be addressed to C. Aye; moc.liamg@eya.wahc

Received 12 December 2016; Accepted 6 March 2017; Published 13 March 2017

Academic Editor: Daniela M. Cirillo

Copyright © 2017 C. Aye et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mycotic pseudoaneurysm of aorta following cardiac surgery is rare but is highly fatal if it is unrecognized and untreated. Here, we report a case of a 45-year-old male patient who presented with rapidly progressive multiple pseudoaneurysms of the ascending aorta infected with multidrug resistant (MDR) Pseudomonas aeruginosa at 5 weeks after cardiac transplantation, on a background of prior bridging therapy with left ventricular assistant device (LVAD). The patient was successfully treated with the newer cephalosporin, Ceftolozane/Tazobactam, in combination with surgery. This is the first reported case of mycotic pseudoaneurysm infected with MDR Pseudomonas. This case also highlights the importance of high vigilance and timely multimodality treatment in the diagnosis and management of mycotic pseudoaneurysm following cardiac transplant, especially in patients who had LVAD.