Case Report

Successful Management of Cryptococcal Meningitis and Bone Marrow Infiltration in a Young HIV/AIDS Patient: A Case Report and Review of the Literature

Table 1

Reported treatments for C. neoformans infection in the bone marrow of HIV patients.

StudyPatient demographicsDiagnosisTreatment for cryptococcosisSurvival to hospital discharge?

Serrano Ocana et al [4]20-year-old African American femaleHIV, C. neoformans meningitis, and C. neoformans in bone marrowAmphotericin B 0.8 mg/kg/day IV for 2 weeks and fluconazole 10 mg/kg/day for 8 weeksYes
Friedman et al [5]12-year-old Thai maleHIV, C. neoformans, and Salmonella enteritis group D in bone marrowAmphotericin B 1 mg/kg/day for 2 weeks and fluconazole 12 mg/kg/day for 8 weeksYes
Swaminathan et al [3]46-year-old Hispanic maleHIV, Histoplasma, and C. neoformans in bone marrowAmphotericin B 1 mg/kg/day IVNo

C. neoformans: Cryptococcus neoformans. Amphotericin B deoxycholate formulation was used in all studies above.