Disseminated Cryptococcosis in a Non-HIV Patient in Singapore

Table 4

Repeated microbiological investigations after 10 days of treatment.

Test	Findings
Serum CRAG	Titer ≥ 1 : 2560
Blood fungal culture	Negative after 8 days of starting combination antifungals
Lumbar puncture
Opening pressure	15.0 cm water
CSF gram stain	Encapsulated blasticonidia (yeasts)
CSF fungal microscopy	Encapsulated blasticonidia seen, morphology suggestive of Cryptococcus
CSF CRAG	Titer ≥ 1 : 2560
CSF fungal culture	CN
CSF aerobic culture	CN