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| Reference (year of publication) | Patient age, sex | Clinical presentation | Past medical history | Concomitant endocarditis | Bacteremia | Vertebral infection site | Positive microbiological specimens | Methods for microbial identification | Microbiological identification | Antibiotic regimen | Total duration of treatment | Spinal surgical intervention | Outcome |
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| Our first case (2017) | 50, male | Cardiogenic shock, fever, back pain | None | Yes | Yes | L3-L4, L5-S1 | Blood cultures | Vitek MS | Granulicatella adiacens | Vancomycin + ceftriaxone + gentamycin for 2 weeks, ceftriaxone for 2 weeks, amoxicillin po for 2 weeks | 6 weeks | No | Cured |
| Our second case (2017) | 47, male | Fever, back pain | Hypertension, L5 disc herniation | No | Yes | L5-S1 | Blood cultures | Vitek MS | Granulicatella adiacens | Vancomycin + ceftriaxone for 1 week, ceftriaxone for 3 weeks, amoxicillin po for 2 weeks | 6 weeks | No | Cured |
| Our third case (2018) | 75, female | Back pain | Previous mitral valvuloplasty | No | Yes | L4-L5 | Blood cultures + bone biopsy | Vitek MS | Abiotrophia defectiva | Vancomycin for 2 weeks, teicoplanin for 6 weeks | 8 weeks | No | NA |
| [15] (2017) | 54, female | Fever, back pain | Patent ductus arteriosus | No (pulmonary artery endoarteritis) | Yes | L5-S1 | Blood cultures | Vitek 2 system + 16S rNA sequencing | Abiotrophia defectiva | Penicillin G + gentamicin | Planned 6 weeks | No | NA |
| [13] (2017) | 48, male | Back pain | Intravenous drug abuse, mitral valve prolapse, HCV infection | No | No | L3-L4 + L3-L5 epidural phlegmon | Vertebral, disk and paraspinal muscles biopsy | ND | Granulicatella/Abiotrophia spp. | Vancomycin for 6 weeks + cefepime in the first day | 6 weeks | No | Cured |
| [12] (2017) | 61, male | Back pain | Diabetes, hypertension | No | No | L3-L4 | Disk biopsy | Vitek 2 system | Granulicatella adiacens | Ceftriaxone + gentamycin for 6 weeks | 6 weeks | No | Cured |
| [11] (2016) | 46, male | Back pain | Diabetes, recent dental procedure | No | No | L2 inferior endplate | Bone biopsy | PCR (not specified) | Granulicatella adiacens | Vancomycin for 6 weeks | 6 weeks | Yes (L1-L3 fixation and interbody cage position in L2) | Cured |
| [10] (2015) | 62, male | Back pain, fever | Hypertension | No | Yes | T10-T12 with spinal abscess | Blood cultures | ND | Abiotrophia adiacens | Vancomycin for 6 weeks | 6 weeks | Yes (laminectomy with T9-L2 fusion surgery) | Cured |
| [9] (2013) | 48, female | Back pain, fever | Parkinson’s disease | No | Yes | L3-L5 | Blood cultures + disk biopsy | 16S rNA sequencing | Abiotrophia adiacens | Ampicillin for 6 weeks | 6 weeks | No | Cured |
| [8] (2010) | 73, male | Back pain, fever | Hypertension, hyperlipidemia | No | Yes | L3-L4 | Blood cultures | Vitek 2 system + 16S rNA sequencing | Granulicatella adiacens | Penicillin G + gentamicin for 6 weeks, po amoxicillin for 9 weeks | 15 weeks | No | Cured |
| [14] (2005) | 51, male | Back pain | Mitral valvulopathy, recent dental procedure | No | Yes | L2-L3, L5-S1, right sacroiliac joint | Blood cultures | 16S rNA sequencing | Abiotrophia defectiva | Amoxicillin + gentamicin (stopped on day 5) + oral rifampicin, po amoxicillin for 11 weeks + po rifampicin for 10 weeks | 14 weeks | No | Cured |
| [7] (2002) | 68, male | Back pain, fever | Diabetes, coronary artery disease, infrarenal aorta prosthetic replacement, AF and AV block with VVI PM | Yes (PM lead) | Yes | T10-T11 | Blood cultures | bioMérieux Rapid ID 32 Strep system | Granulicatella adiacens | Penicillin + gentamicin + rifampin | ND | No | Cured |
| [6] (1998) | 45, male | Back pain, fever | ND | Yes | Yes | L2-L4 | Blood cultures | ND | Abiotrophia adiacens | Penicillin for 2 weeks, po clindamycin for 2 weeks | 4 weeks | No | Cured |
| [6] (1998) | 50, male | Back pain, fever | ND | Yes | Yes | L3-L5 | Blood cultures | ND | Abiotrophia adiacens | Penicillin + gentamicin for 2 weeks, ceftriaxone for 2 weeks | 4 weeks | No | Cured |
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