Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis

Figure 2

Neighbor-joining phylogenetic tree based on 2,464 unique, core genome biallelic single nucleotide (SNP) differences relative to the reference, MGAS27061, between case (circled) and CDC-sequenced emm89 iGAS strains from 2015 [4]. GAS isolates from cases of toxic shock are depicted by boxes including 2 from the 2015 CDC-sequenced strains and 2 previously described isolates from Houston, TX.