Plasmodium vivax Infection in Multiple Family Members in Texas, USA

Table 1

Clinical and laboratory characteristics of the patients.

	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Patient 6
Age (years)	7	7	11	2.8	5	6
Gender	Female	Male	Male	Male	Female	Female
Family	A	A	B	A	B	B
Relation to patient 1		Twin brother	Cousin	Sibling of patient 1 and 2	Sibling of patients 3	Sibling of patients 3 and 5
Day of presentation	Day 1	Day 5	Day 9	Day 15	Day 41	Day 55
Presenting symptoms	Fever, chills, headache, and myalgia	Fever, myalgia, and fatigue	Fever, chills, nausea, and fatigue	Fever, chills, emesis, headache, and myalgia	Fever, fatigue, emesis, and abdominal pain	Fever, nausea, emesis, headache, and cough
Organomegalies	None	None	None	None	None	Mild splenomegaly
Hemoglobin (g/dl)	9.4	11.2	13.7	11.3	11.3	11.2
Platelets (per mm^3)	51,000	87,000	152,000	99,000	108,000	69,000
Initial parasitemia (%)	0.25	0.11	1.3	2.4	5	1.2
Period between immigration to US and illness	∼6 months	∼6 months	∼9 months	∼6 months	∼10 months	∼10.5 months
Previous malaria history	Yes	Yes	Yes	Yes	Yes	Yes
Previous blood transfusion or travel outside Houston since immigration	No	No	No	No	No	No
Parasitemia (%); time after treatment	0.1, 3 days	Not done	Negative, 7 days	0.5, 2 days; negative, 65 days	Negative, 5 days	0.01, 25 days

All patients are previously healthy except patient 4 (history of idiopathic thrombocytopenic purpura).