Intoxication after Extreme Oral Overdose of Quetiapine to Attempt Suicide: Pharmacological Concerns of Side Effects

Figure 1

Serum time-concentration profile of quetiapine after ingestion of an assumed amount of 36 g Seroquel in a 32-year-old female patient. Solid-line: fitted line based on a two-compartment model assuming a reduced resorption. Dotted line: fitted line expected by population pharmacokinetic parameters and normal resorption.