Intoxication after Extreme Oral Overdose of Quetiapine to Attempt Suicide: Pharmacological Concerns of Side Effects

Table 1

Parameter	Time after ingestion of quetiapine
	26 h	28 h	29 h	32 h	37 h	51	62 h	140 h	331 h
Laboratory data:
Quetiapine, $\mu$g/L		4220		2770		64	64
Na^+, mmol/L			137		140		141	138	138
K^+, mmol/L			3.6		4.6		4.0	3.6	4.3
Cl^-, mmol/L					123		116	105	105
Glucose, mmol/L	8.96		8.12		5.94		5.04	5.66	5.49
CK, U/L			333		317		355	69	66
Leucocytes ($\times {10}^9$/L)			12.06		6.61		6.23	6.21	5.46
CRP, mg/L			32		76		96	11	<3
Free T3, ng/L			2.8		2.1		2.6
Free T4, ng/L			18.6		14.1		12.0
TSH, mU/L			6.04		8.56		3.35
Vital parameters:
BP syst., mmHg	127		110		120		130	130
BP diast., mmHg	83		70		80		70	70
HR, beats/min	140		120		90		85	85
RR, resp./min	12		12		8		8
QTc [ms]					436		404		388

CK: creatin kinase, CRP: c-reactive protein, T3: triiodothyronine, T4: tetraiodothyronine, TSH: thyroid-stimulating hormone, BP: blood pressure, HR: heart rate, RR: respiratory rate, QTc: cardiac QT interval (at a standardized heart rate of 60/minute).