Case Report

The Response of Hemostatic Marker Levels to Activated Factor VII in a Neonate following Cardiopulmonary Bypass

Table 1

Changes in Marker levels from before and after rFVIIa. nM: nanomolar. pM: picomolar. F1.2: prothrombin activation fragment. tat: thrombin antithrombin complex. dd: d-dimer. apai: active plasminogen activator inhibitor type 1. atpa: active tissue plasmingoen activator. TP8: Time point 8, after protamine or baseline for this report. TP9: Time point 9, 1 hour after surgery or after rFVIIa, if applicable.

Patient receiving rFVIIa?F1.2 (nM)TAT (pM)DD (pM)apai (pM)atpa (pM)

TP8 baselineTP9TP8 baselineTP9TP8 baselineTP9TP8 baselineTP9TP8 baselineTP9

No3.86.950551444193222218.71524.573.41.3
No23356342737154014.51013.3120.82
Yes52753619272364308180.4453.1105.84.2