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Case Reports in Medicine
Volume 2009, Article ID 687285, 4 pages
http://dx.doi.org/10.1155/2009/687285
Case Report

Benzylthiouracil-Induced Glomerulonephritis

1Department of Endocrinology, Farhat Hached Hospital, 4000 Sousse, Tunisia
2Department of Internal Medicine, Sahloul Hospital, Sousse, Tunisia

Received 22 April 2009; Accepted 5 June 2009

Academic Editor: Shern L. Chew

Copyright © 2009 Sihem Trimeche Ajmi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. MC. Slot, TP. Links, CA Stegeman, and JW. Tervaert , “Occurrence of antineutrophil cytoplasmic antibodies and associated vasculitis in patients with hyperthyroidism treated with antithyroid drugs: A long-term followup study,” Arthritis Rheum, vol. 53, no. 1, pp. 108–13, 2005. View at Google Scholar
  2. D. Zimmerman and A. N. Lteif, “Thyrotoxicosis in children,” Endocrinology and Metabolism Clinics of North America, vol. 27, no. 1, pp. 109–126, 1998. View at Publisher · View at Google Scholar
  3. S. J. Stankus and N. T. Johnson, “Propylthiouracil-induced hypersensitivity vasculitis presenting as respiratory failure,” Chest, vol. 102, no. 5, pp. 1595–1596, 1992. View at Google Scholar
  4. J. E. Gunton, J. Stiel, P. Clifton-Bligh, E. Wilmshurst, and A. McElduff, “Prevalence of positive anti-neutrophil cytoplasmic antibody (ANCA) in patients receiving anti-thyroid medication,” European Journal of Endocrinology, vol. 142, no. 6, pp. 587–590, 2000. View at Google Scholar
  5. N. Tieulie, H. Du Le Thi, M. Andreu et al., “Glomérulonéphrite associée aux ANCA secondaire au benzylthiouracile,” Revue de Medecine Interne, vol. 23, pp. 853–856, 2002. View at Google Scholar
  6. H. Kaaroud, K. Khiari, F. Ben Moussa, S. Barbouch, E. Boussema, and H. Ben Maïz, “Une vascularite associant une atteinte rénale et pulmonaire au cours d'une maladie de Basedow traitée par le benzylthiouracile,” Revue de Medecine Interne, vol. 23, no. 10, pp. 857–861, 2002. View at Publisher · View at Google Scholar
  7. F. Jarraya, M. Abid, R. Jlidi et al., “Myeloperoxidase-antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis associated with benzylthiouracil therapy,” Nephrology Dialysis Transplantation, vol. 18, no. 11, pp. 2421–2423, 2003. View at Publisher · View at Google Scholar
  8. M. Hachicha, T. Kammoun, W. Ben Romdhane et al., “Vasculitis with renal involvement and antineutrophil cytoplasmic antibodies (ANCA) in a child receiving benzylthiouracil,” Néphrologie & Thérapeutique, vol. 3, no. 4, pp. 147–151, 2007. View at Publisher · View at Google Scholar
  9. K. M. Dolman, R. O. B. Gans, T. J. Vervaat et al., “Vasculitis and antineutrophil cytoplasmic autoantibodies associated with propylthiouracil therapy,” The Lancet, vol. 342, no. 8872, pp. 651–652, 1993. View at Publisher · View at Google Scholar
  10. B. A. Vogt, Y. Kim, J. C. Jennette, R. J. Falk, B. A. Burke, and A. Sinaiko, “Antineutrophil cytoplasmic autoantibody-positive crescentic glomerulonephritis as a complication of treatment with propylthiouracil in children,” Journal of Pediatrics, vol. 124, no. 6, pp. 986–988, 1994. View at Publisher · View at Google Scholar
  11. B. A. Vogt, Y. Kim, J. C. Jennette, R. J. Falk, B. A. Burke, and A. Sinaiko, “Antineutrophil cytoplasmic autoantibody-positive crescentic glomerulonephritis as a complication of treatment with propylthiouracil in children,” Journal of Pediatrics, vol. 124, no. 6, pp. 986–988, 1994. View at Publisher · View at Google Scholar
  12. M. Tanemoto, H. Miyakawa, J. Hanai, M. Yago, M. Kitaoka, and S. Uchida, “Myeloperoxidase-antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis complicating the course of Graves' disease: report of three adult cases,” American Journal of Kidney Diseases, vol. 26, no. 5, pp. 774–780, 1995. View at Google Scholar
  13. D. D'Cruz, A. M. S. Chesser, C. Lightowler et al., “Antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis associated with anti-thyroid drug treatment,” British Journal of Rheumatology, vol. 34, no. 11, pp. 1090–1091, 1995. View at Google Scholar
  14. Y. Hori, K. Arizono, S. Hara, R. Kawai, M. Hara, and A. Yamada, “Antineutrophil cytoplasmic autoantibody-positive crescentic glomerulonephritis associated with thiamazole therapy,” Nephron, vol. 74, no. 4, pp. 734–735, 1996. View at Google Scholar
  15. W. G. Couser, “Rapidly progressive glomerulonephritis: classification, pathogenetic mechanisms, and therapy,” American Journal of Kidney Diseases, vol. 11, no. 6, pp. 449–464, 1988. View at Google Scholar
  16. W. R. Griswold, S. A. Mendoza, W. Johnston, and S. Nichols, “Vasculitis associated with propylthiouracil,” Western Journal of Medicine, vol. 128, no. 6, pp. 543–546, 1978. View at Google Scholar
  17. F. G. Cassorla, D. N. Finegold, J. S. Parks et al., “Vasculitis, pulmonary cavitation, and anemia during antithyroid drug therapy,” American Journal of Diseases of Children, vol. 137, no. 2, pp. 118–122, 1983. View at Google Scholar
  18. Y. Kudoh, S. Kuroda, K. Shimamoto, and O. Iimura, “Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies,” Clinical Nephrology, vol. 48, no. 1, pp. 41–43, 1997. View at Google Scholar
  19. J. E. Gunton, J. Stiel, R. J. Caterson, and A. McElduff, “Anti-thyroid drugs and antineutrophil cytoplasmic antibody positive vasculitis. A case report and review of the literature,” The Journal of Clinical Endocrinology & Metabolism, vol. 84, no. 1, pp. 13–16, 1999. View at Publisher · View at Google Scholar
  20. D. S. Cooper, “Antithyroid drugs,” The New England Journal of Medicine, vol. 311, no. 21, pp. 1353–1362, 1984. View at Google Scholar
  21. H. Sato, M. Hattori, M. Fujieda et al., “High prevalence of antineutrophil cytoplasmic antibody positivity in childhood onset Graves' disease treated with propylthiouracil,” The Journal of Clinical Endocrinology & Metabolism, vol. 85, no. 11, pp. 4270–4273, 2000. View at Publisher · View at Google Scholar
  22. Y. Gao, M.-H. Zhao, X.-H. Guo, G. Xin, Y. Gao, and H.-Y. Wang, “The prevalence and target antigens of antithyroid drugs induced antineutrophil cytoplasmic antibodies (ANCA) in Chinese patients with hyperthyroidism,” Endocrine Research, vol. 30, no. 2, pp. 205–213, 2004. View at Publisher · View at Google Scholar
  23. D. C. C. Lam and R. H. Lindsay, “Accumulation of 2-14C propylthiouracil in human polymorphonuclear leukocytes,” Biochemical Pharmacology, vol. 28, no. 15, pp. 2289–2296, 1979. View at Publisher · View at Google Scholar
  24. E. Lee, M. Hirouchi, M. Hosokawa, H. Sayo, M. Kohno, and K. Kariya, “Inactivation of peroxidases of rat bone marrow by repeated administration of propylthiouracil is accompanied by a change in the heme structure,” Biochemical Pharmacology, vol. 37, no. 11, pp. 2151–2153, 1988. View at Publisher · View at Google Scholar
  25. A.-M. Haapala, E. Soppi, H. Hyoty, J. Mustonen, and A. Pasternack, “Cross-reactivity between antibodies to thyroid microsomal antigens and myeloperoxidase,” The Lancet, vol. 337, no. 8744, p. 803, 1991. View at Google Scholar
  26. T. Kitahara, K. Hiromura, A. Maezawa et al., “Case of propylthiouracil-induced vasculitis associated with anti-neutrophil cytoplasmic antibody (ANCA): review of literature,” Clinical Nephrology, vol. 47, no. 5, pp. 336–340, 1997. View at Google Scholar
  27. M. Tanemoto, H. Miyakawa, J. Hanai, M. Yago, M. Kitaoka, and S. Uchida, “Myeloperoxidase-antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis complicating the course of Graves' disease: report of three adult cases,” American Journal of Kidney Diseases, vol. 26, no. 5, pp. 774–780, 1995. View at Google Scholar
  28. S. Yuasa, M. Hashimoto, T. Yura et al., “Antineutrophil cytoplasmic antibodies (ANCA)-associated crescentic glomerulonephritis and propylthiouracil therapy,” Nephron, vol. 73, no. 4, pp. 701–703, 1996. View at Google Scholar
  29. K. Kanahara, N. Yorioka, C. Nakamura et al., “Myeloperoxidase-antineutrophil cytoplasmic antibody-associated glomerulonephritis with membranous nephropathy in remission,” Internal Medicine, vol. 36, no. 11, pp. 841–846, 1997. View at Google Scholar
  30. S. Otsuka, A. Kinebuchi, H. Tabata, A. Yamakage, and S. Yamazaki, “Myeloperoxidase-antineurotrophil cytoplasmic antibody-associated vasculitis following propylthiouracil therapy,” British Journal of Dermatology, vol. 142, no. 4, pp. 828–830, 2000. View at Publisher · View at Google Scholar
  31. L. Harper, P. Cockwell, and C. O. S. Savage, “Case of propylthiouracil-induced ANCA associated small vessel vasculitis,” Nephrology Dialysis Transplantation, vol. 13, no. 2, pp. 455–458, 1998. View at Google Scholar