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Case Reports in Medicine
Volume 2009 (2009), Article ID 693014, 3 pages
Case Report

Profound Muscle Weakness and Pain after One Dose of Actonel

Neurology Clinical Trials Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA

Received 15 July 2009; Accepted 18 September 2009

Academic Editor: Mamede de Carvalho

Copyright © 2009 Irina Badayan and Merit E. Cudkowicz. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The World Health Organization (WHO) defines osteopenia as a bone density between 1 and 2.5 standard deviation (SD) below the bone density of a normal young adult Iqbal 2000. Osteoporosis is defined as 2.5 SD or more below that reference point Iqbal 2000. Bisphosphonates are a group of medications used to treat osteoporosis, Padget's disease of bone, and osteopenia. We report a woman who developed profound muscle weakness and pain after one dose of Risedronate (Actonel).