Two Adults with Adrenal Myelolipoma and 21-Hydroxylase Deficiency

Table 1

Myelolipoma: baseline measurements and endocrinological test results.

	Patient 1	Patient 2	Normal
Baseline
ACTH, pmol/L	6–32.8*	10.9–94.2	(2–13)
Cortisol, nmol/L	210	387	(250–750)
17 OH-progesterone, nmol/L	$>$605	445	($<$6)
DHEAS, $\mu$mol/L	14.4	1.8	(6–12)
Androstendione, nmol/L	43.8	10.9	($<$5.6)
Testosterone, nmol/L	11.7	10.1	(10–40)
ACTH stimulation^**
Cortisol 30 minutes, nmol/L	211	409
Cortisol 60 minutes, nmol/L	231	412	($>$550)
17 OH-progesterone 30 minutes, nmol/L	$>$605	445
17 OH-progesterone 60 minutes, nmol/L	$>$605	560	($<$30)
Dexamethasone suppression^***
Cortisol, nmol/L	22	45	(<50)
17 OH-progesterone, nmol/L	14.3	18.8

*Most values in the higher range. ^**Corticotropin (250 ug i.v.). ^***1 mg overnight test in Patient 2 and 0.5 mg $\times$ 4 for 2 days in Patient 1.