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Case Reports in Medicine
Volume 2010, Article ID 136823, 2 pages
http://dx.doi.org/10.1155/2010/136823
Case Report

Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy

1Cedars-Sinai Medical Center, 8700 W Beverly Bowerard, Los Angeles, CA 90048, USA
2LAC+USC Medical Center, 1420 S Central Avenue, Glendale, CA 91201, USA

Received 21 April 2010; Accepted 18 August 2010

Academic Editor: William Hurd

Copyright © 2010 Beni Adegoke Adeniji et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. We present a successful case of laparoscopic splenectomy for a massively enlarged spleen at 25 weeks of gestation for hairy cell leukemia in pregnancy in a woman with initial hemoglobin of 4.3 gm/dl and platelet count of 18,000/mm3. Study Design. Case report. Results. This report provides an approach to management that may be applicable in those cases where thrombocytopenia or other clinical imperatives preclude delaying treatment till after pregnancy. Conclusion. Hairy cell leukemia is a clonal B-Cell malignancy, for which there is very limited experience worldwide for its management when it occurs during pregnancy. Laparoscopic splenectomy should be considered as a therapeutic option, even with a significantly enlarged spleen, in order to avoid the risks of fetal exposure to chemotherapeutic agents. Unique considerations relating to pregnancy are highlighted.