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Case Reports in Medicine
Volume 2010, Article ID 176514, 2 pages
Case Report

Keratouveitis as a First Presentation of Relapsing Polychondritis

Department of Ophthalmology, Whipps Cross University Hospital, London E11 1NR, UK

Received 13 July 2010; Accepted 27 September 2010

Academic Editor: C. G. M. Kallenberg

Copyright © 2010 Ahmed Sallam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper provides images and a description of an unusual manifestation of relapsing polychondritis presenting initially with isolated ocular signs, mimicking infective keratitis. We present an interventional case report of a 75-year-old man who presented with marked left ocular irritation and photophobia. Ophthalmological examination disclosed corneal intrastromal infiltrate and hypopyon which failed to respond to intensive antimicrobial drops. He later went on to develop bilateral auricular chondritis. Relapsing polychondritis was diagnosed. Treatment with topical and oral corticosteroids resulted in marked improvement of the corneal infiltrate and resolution of the auricular inflammation. The paper highlights the importance of considering connective tissue inflammatory conditions in any stromal keratitis unresponsive to antimicrobial treatment.