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Case Reports in Medicine
Volume 2010 (2010), Article ID 235295, 3 pages
http://dx.doi.org/10.1155/2010/235295
Case Report

Nonleukemic Granulocytic Sarcoma of Knee: A Case Report

Department of Medical Oncology, National Institute of Oncology, Allal El-Fassi Street, Rabat, Morocco

Received 28 September 2010; Accepted 18 November 2010

Academic Editor: Werner Rabitsch

Copyright © 2010 Ibrahim Elghissassi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Granulocytic sarcoma (GS) is a rare extramedullary tumor composed of immature myeloid cells. It is usually associated with leukemia or other myeloproliferative disorders. It occurs very rarely without overt hematologic diseases. A 19-year-old man presented with left knee mass. Biopsy with pathological analysis showed lymphoma aspect. Immunostains yielded the diagnosis of GS with myeloperoxidase and CD43 positivity. There was no systemic manifestation of leukemia, and bone marrow biopsiy was negative for neoplastic infiltration. Chemotherapy by CHOP was efficient, and the patient remaind alive and healthy 40 months after the end of treatment. The case is discussed in the framework of the existing literature about the diagnosis, treatment, and prognosis of this very rare condition.