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Case Reports in Medicine
Volume 2010, Article ID 453624, 4 pages
http://dx.doi.org/10.1155/2010/453624
Case Report

Two Cases of Small Cell Carcinoma of the Gallbladder

Department of General Surgery, Center for Minimally Invasive Surgery, The Ohio State University Medical Center, Columbus, OH 43210, USA

Received 20 July 2010; Accepted 27 September 2010

Academic Editor: Michael Hünerbein

Copyright © 2010 Peter Nau et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Small cell carcinoma of the gallbladder is a rare disease process with approximately 40 cases reported in the literature. It is most often found in elderly female population and is associated with cholelithiasis and cigarette smoking. A multidisciplinary approach to treatment with wide surgical resection and adjuvant chemotherapy is the current standard of care. Notwithstanding prompt medical intervention, it is a disease with a poor prognosis. The pathology is characterized by early metastases and extensive local invasion. Herein, we report two cases of small cell carcinoma addressed at our institution. In both cases, a radical resection was performed with subsequent referral to oncology for additional therapy.