Case Report

Prolonged Neuromuscular Blockade Following Succinylcholine Administration to a Patient with a Reduced Butyrylcholinesterase Activity

Table 1

Genotypeβ€”Phenotype Relation of Butyrylcholinesterase (BCHE).

Nucleotide ExchangeAmino Acid ChangePhenotype VariantsReference

9 8 A > 𝐺 Tyr-33-CysSilent [1]
1 0 9 C > 𝑇 Pro-37-SerSilent [1]
2 0 9 A > 𝐺 Asp-70-GlyAtypical[2]
3 5 0 T > 𝐴 𝐺 Gly-117-Gly+Silent[3]
3 5 5 C > 𝑇 Gln-119-STOPSilent[4]
3 7 5 A > 𝑇 Leu-125-PheSilent [1]
3 8 3 A > 𝐺 Tyr-128-CysSilent[5]
4 2 4 G > 𝐴 Val-142-MetH[6]
5 1 0 T > 𝐺 Asp-170-GluSilent [1]
5 5 1 C > 𝑇 Ala-184-ValFluoride-Resistant [7, 8]
5 9 2 A > 𝐺 Ser-198-GlySilent [1]
5 9 6 C > 𝑇 Ala-199-ValSilent[9]
6 0 1 G > 𝐴 Ala-201-ThrSilent [1]
7 2 8 C > 𝑇 Thr-243-MetFluoride-Resistant[10]
8 1 1 G > 𝑇 Glu-271-STOPSilent [1]
1 0 9 3 G > 𝐴 Gly-365-ArgSilent[11]
1 1 6 9 G > 𝑇 Gly-390-ValFluoride-Resistant[10]
1 2 9 4 G > 𝑇 Glu-432-STOP[7]
1 4 1 1 T > 𝐢 Trp-471-ArgSilent [1]
1 4 9 0 A > 𝑇 Glu-497-ValJ[12]
1 5 0 0 T > 𝐴 Tyr-500-STOPSilent [1]
1 5 4 3 C > 𝑇 Arg-515-CysSilent[11]
1 5 5 3 A > 𝑇 Gln-518-LeuSilent [1]
1 6 1 5 G > 𝐴 Ala-539-ThrK[13]