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Case Reports in Medicine
Volume 2010, Article ID 517178, 3 pages
http://dx.doi.org/10.1155/2010/517178
Case Report

X-Linked Lymphoproliferative Disease Presenting as Pancytopenia in a 10-Month-Old Boy

Departments of Pediatrics and Internal Medicine, University of South Carolina School of Medicine, 14 Medical Park Suite 400, Columbia, SC 29203, USA

Received 10 February 2010; Accepted 14 April 2010

Academic Editor: Abhay R. Satoskar

Copyright © 2010 S. Nicole Chadha and David Amrol. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

X-linked lymphoproliferative disease, also known as Duncan's syndrome, is a rare genetic disorder that causes exaggerated immune responses to Epstein-Barr virus (EBV) infection and often leads to death. Patient presentation varies but can include signs and symptoms typical of EBV, pancytopenia, and fulminant hepatitis.