Case Report

Rapidly Evolving Giant Dermatofibroma

Figure 4

On low power the lesion is composed of spindled cells in the dermis with a well defined Grenz zone; H&E stain, moderate magnification × 40. On high power, bundles of interlacing spindle cells in the dermis. H&E stain, magnification × 100. Same area of lesion as in (b) stained for Factor XIIIa, showing diffuse staining with scattered strongly positive cells; Factor XIIIa stain, magnification × 100. High powered section of specimen showing cholesterol clefting and scattered giant cells; H&E stain, magnification × 100
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(a)
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(b)
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(c)
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(d)