Case Report

Immunotherapy Responsive Autoimmune Subacute Encephalitis: A Report of Two Cases

Figure 1

MRI findings in two cases of immunotherapy responsive autoimmune subacute encephalitis. Brain MRI of Patient 1 ((a), (b)) with immunotherapy responsive voltage-gated potassium channel antibody and antithyroperoxidase antibody-associated subacute encephalitis illustrates increased signal in the bilateral medial temporal lobes on T2 fluid attenuated inversion recovery (T2 FLAIR) sequences ((a) initial image). Follow up image after 8 months (b) was unchanged. Brain MRI of case 2 illustrates increased signal in the bilateral medial temporal lobes on T2 FLAIR ((c) initial image) and after 13 months (d) shows its resolution; T1 with contrast sequence ((e) initial image) shows bilateral temporal atrophy and after 13 months (f) showing persistent bilateral frontotemporal atrophy.
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(a)
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(b)
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(c)
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(d)
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(e)
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(f)