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Case Reports in Medicine
Volume 2010, Article ID 970805, 3 pages
Case Report

Xanthogranulomatous Salpingitis Associated with a Large Uterine Leiomyoma

1Michael G. DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada
2Department of Pathology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada

Received 16 June 2010; Revised 15 September 2010; Accepted 29 September 2010

Academic Editor: A. R. Satoskar

Copyright © 2010 Joanne Margaret Howey et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A case of xanthogranulomatous salpingitis (XGS) associated with a large uterine leiomyoma in a 50-year-old woman is presented. Xanthogranulomatous inflammation is an uncommon form of chronic inflammation that is destructive to affected organs. It is characterized by the presence of lipid-filled macrophages with admixed lymphocytes, plasma cells, and neutrophils. A review of the literature revealed that most patients with XGS have a clinical history of long-standing pelvic inflammatory disease (PID) or, less often, endometriosis. We report a case lacking a history of either PID or endometriosis but with a concurrent large uterine leiomyoma. Although the exact etiology in this case was not clear, the leiomyoma may have played a contributory role in pathogenesis.