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Case Reports in Medicine
Volume 2011, Article ID 134801, 3 pages
Case Report

Primary Malignant Fibrous Histiocytoma: A Rare Case

1Department of Surgery, “Agios Dimitrios” General Hospital of Thessaloniki, 54634 Thessaloniki, Greece
2Laboratory of Anatomy, Department of Physical Education and Sports Medicine (at Serres), “Aristotelian” University of Thessaloniki, 62100 Serres, Greece

Received 25 June 2011; Accepted 12 August 2011

Academic Editor: Michael N. Varras

Copyright © 2011 Anastasios Katsourakis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Malignant fibrous histiocytoma (MFH) of the small intestine is an extremely rare condition. It occurs most commonly in the extremities and the trunk. We report a case of a 67-year-old woman who admitted with fever, myalgia, and altered status. After thorough investigation, a tumor of the jejunum was found. The patient underwent complete surgical removal of the tumor. A diagnosis of MFN (undifferentiated high-grade pleomorphic sarcoma) was made. The patient received adjuvant chemotherapy with Gemcitabine. Two years after the operation, the patient died due to recurrence of the disease. MFH of the small intestine is an extremely rare neoplasm with an aggressive biological behaviour. In this paper, pathogenesis, natural history, and treatment are reviewed.