Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol

Table 2

Initial blood gas results.

Time since admission to ED in hours	pH	BE	Bicarbonate	PCO2	PaO2	Lactate
In ED venous gas recorded	7.371	−2.3
5 hours post ED	7.3	−3.9	21	7.49	7.9
11:25—on trauma mask	7.34	−6.2	19.3	4.84	9.37	1.79
12:00—now on NIV	7.36	−5.8	19.5	4.52	7.83	2.5
13:00	7.3	−9.4	16.8	4.49	9.56	2.5
17:00	7.26	−10.4	16	4.7	9.43	6.44
18:00	7.27	−10.3	16.1	4.54	8.26	5.87
19:30	7.26	−11.2	15.5	4.5	10.00	6.25
20:54—bicarbonate started on basis of this gas—50 mLs/hr of 8.4%; Total 200 mLs given	7.25	−13.3	14	3.95	10.89	7.78
22:54	7.31	−10.1	16.2	3.93	7.83	6.27
23:57	7.32	−8.0	17.9	4.53	9.47	4.23
25:00	7.35	−6.2	19.3	4.51	8.58	3.63
26:06	7.34	−6.0	19.5	4.96	10.08	2.89
27:01	7.33	−5.8	19.7	4.91	9.73	2.40
28:26	7.33	−5.7	19.7	4.97	9.64	2.05
29:32	7.34	−5.1	20.1	4.95	9.11	1.77