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Case Reports in Medicine
Volume 2011 (2011), Article ID 293076, 4 pages
http://dx.doi.org/10.1155/2011/293076
Case Report

Harlequin Syndrome in a Case of Toxic Goitre: A Rare Association

1Department of Endocrine Surgery, Narayana Medical College & Superspeciality Hospital, Chinthareddypalem, Nellore, Andhra Pradesh 524002, India
2Department of Anesthesiology, Narayana Medical College & Superspeciality Hospital, Chinthareddypalem, Nellore, Andhra Pradesh 524002, India

Received 19 April 2011; Revised 30 May 2011; Accepted 30 May 2011

Academic Editor: Michael G. Irwin

Copyright © 2011 P. V. Pradeep et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Harlequin syndrome (HS) is known to be associated with conditions like brain stem infarcts and superior mediastinal neurinoma. However, it has not been reported in association with autoimmune hyperthyroidism. We report a case of exacerbation of unilateral sweating in a patient with HS following the onset of toxic goitre. Previous reports have suggested that a tortuous inferior thyroid artery can produce neurovascular compression of the sympathetic chain which was not observed in our patient. Autoimmune aetiology for HS needs to be explored. Increased sweating in hyperthyroid patients needs to be assessed properly so as to prognosticate appropriately.