Primary Colorectal Adenocarcinoma Metastatic to the Breast: Case Report and Review of Nineteen Cases
Figure 2
(a, b) The breast biopsy demonstrated an invasive adenocarcinoma with a focal cribriform pattern, hyperchromatic round to oval nuclei, and brisk mitotic activity (H&E, 100x, 200x). (c) Cytokeratin 20 showed diffuse, positive staining in the tumor (cytokeratin 20, 100x). (d) CDX2, specific for intestinal epithelium, exhibited diffuse nuclear immunoreactivity in the tumor cells (CDX2, 200x).
