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Case Reports in Medicine
Volume 2011 (2011), Article ID 748194, 4 pages
http://dx.doi.org/10.1155/2011/748194
Case Report

Primitive Neuroectodermal Tumor of the Liver: A Case Report

1Department of Pathology, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, Brazil
2Department of Surgery, Nossa Senhora da Conceição Hospital, Porto Alegre, Rio Grande do Sul, Brazil

Received 5 September 2011; Revised 26 September 2011; Accepted 29 September 2011

Academic Editor: Estella M. Matutes

Copyright © 2011 Eduardo Cambruzzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients.