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Case Reports in Medicine
Volume 2011, Article ID 765645, 3 pages
http://dx.doi.org/10.1155/2011/765645
Case Report

Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report

1Gamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USA
2University of Washington School of Medicine, 1959 N.E. Pacific Street, Seattle, WA 98195, USA
3Department of Natural Sciences, Carroll College, 1601 N Benton Avenue, Helena, MT 59625, USA
4Cancer Care Northwest, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USA
5Providence Sacred Heart Medical Center, 101 W 8th Avenue, Spokane, WA 99204, USA
6MacKay & Meyer MDs, Spokane, WA 99202, USA
7Spokane Brain & Spine, Spokane, WA 99204, USA

Received 1 July 2011; Revised 22 September 2011; Accepted 22 September 2011

Academic Editor: Jahn M. Nesland

Copyright © 2011 Hansi Z. Jiang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We describe the multimodality treatment regimen of a 53-year-old man diagnosed with olfactory neuroblastoma (Kadish stage C) in the right nasal cavity extending into the ethmoid sinus and across the cribriform plate. Endoscopic surgery for tumor resection was followed by a combination of external beam radiotherapy and stereotactic radiosurgery boost with concurrent chemotherapy. The novel combination of dual radiation therapies allowed for the preservation of the nearby optic structures while providing an adequate dosage to a sufficient volume of the afflicted tissue.