Case Report

Hypoglycemic Syndrome in a Patient with Proinsulin-Only Secreting Pancreatic Adenoma (Proinsulinoma)

Table 2

Results of the venous sampling during selective angiography (Imamura test). Normal range for insulin concentration was 43–210 pmol/L (6.0–29.1 mU/L) and for proinsulin concentration was <1.1 pmol/L (10 pg/mL).

Time after Ca2+-gluconate bolus
ArteryAnalyte0′30′60′120′

SplenicInsulin, pmol/L (mU/L)55 (7.6)55 (7.6)62 (8.6)67 (9.3)
Proinsulin, pmol/L (pg/mL)20 (185)20 (176)14 (131)20 (176)
Glucose, mmol/L (mg/dL)3.0 (54)3.1 (55)2.8 (51)2.9 (53)
Distal splenicInsulin43 (6.0)32 (4.4)46 (6.4)65 (9.0)
Proinsulin18 (155)16 (145)15 (132)27 (234)
Glucose3.0 (54)2.4 (43)2.7 (49)3.3 (60)
Superior mesentericInsulin32 (4.5)<14 (2.0)60 (8.3)43 (6.0)
Proinsulin19 (166)22 (192)22 (196)24 (212)
Glucose2.6 (47)2.1 (37)3.1 (55)3.3 (60)
GastroduodenalInsulin53 (7.4)37 (5.1)38 (5.3)42 (5.8)
Proinsulin19 (166)20 (179)18 (163)18 (155)
Glucose2.6 (47)2.8 (50)3.2 (58)3.1 (56)