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Case Reports in Medicine
Volume 2011 (2011), Article ID 953890, 5 pages
http://dx.doi.org/10.1155/2011/953890
Case Report

Thrombotic Thrombocytopenic Purpura Associated with Mixed Connective Tissue Disease: A Case Report

1Faculdade de Medicina de Campos, 28035-580, Campos dos Goytacazes, RJ, Brazil
2Hospital Ferreira Machado and Hospital Geral de Guarus, Campos dos Goytacazes, RJ, Brazil

Received 19 March 2011; Revised 10 July 2011; Accepted 13 July 2011

Academic Editor: G. Pineo

Copyright © 2011 João Tadeu Damian Souto Filho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. L. Allford, B. J. Hunt, P. Rose, and S. J. Machin, “Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias,” British Journal of Haematology, vol. 120, no. 4, pp. 556–573, 2003. View at Google Scholar · View at Scopus
  2. J. N. George, “How I treat patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome,” Blood, vol. 96, no. 4, pp. 1223–1229, 2000. View at Google Scholar · View at Scopus
  3. M. Franchini, “Thrombotic microangiopathies: an update,” Hematology, vol. 11, no. 3, pp. 139–146, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Matsuyama, M. Kuwana, M. Matsumoto, A. Isonishi, S. Inokuma, and Y. Fujimura, “Heterogeneous pathogenic processes of thrombotic microangiopathies in patients with connective tissue diseases,” Thrombosis & Haemostasis, vol. 102, no. 2, pp. 371–378, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. J. N. George, S. K. Vesely, and J. A. James, “Overlapping features of thrombotic thrombocytopenic purpura and systemic lupus erythematosus,” Southern Medical Journal, vol. 100, no. 5, pp. 512–514, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. S. K. Kwok, J. H. Ju, C. S. Cho, H. Y. Kim, and S. H. Park, “Thrombotic thrombocytopenic purpura in systemic lupus erythematosus: risk factors and clinical outcome: a single centre study,” Lupus, vol. 18, no. 1, pp. 16–21, 2009. View at Google Scholar · View at Scopus
  7. T. Zheng, L. Chunlei, W. Zhen et al., “Clinical-pathological features and prognosis of thrombotic thrombocytopenic purpura in patients with lupus nephritis,” American Journal of the Medical Sciences, vol. 338, no. 5, pp. 343–347, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Gopal, C. D. Cohn, M. R. McEntire, and J. B. Alperin, “Thrombotic thrombocytopenic purpura and adult onset still's disease,” American Journal of the Medical Sciences, vol. 337, no. 5, pp. 373–376, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Sayarlioglu, H. Sayarlioglu, M. Ozkaya, O. Balakan, and M. A. Ucar, “Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome and adult onset still's disease: case report and review of the literature,” Modern Rheumatology, vol. 18, no. 4, pp. 403–406, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. S. K. Vesely, J. N. George, B. Lammle et al., “ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients,” Blood, vol. 102, no. 1, pp. 60–68, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. E. M. Kfoury Baz, R. A. Mahfouz, and A. F. Masri, “Thrombotic thrombocytopenic purpura in a patient with rheumatoid arthritis treated by plasmapheresis,” Therapeutic Apheresis, vol. 3, no. 4, pp. 314–316, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. E. M. Kfoury Baz, R. A. Mahfouz, A. F. Masri et al., “Thrombotic thrombocytopenic purpura in a case of scleroderma renal crisis treated with twice-daily therapeutic plasma exchange,” Renal Failure, vol. 23, no. 5, pp. 737–742, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. E. W. Paice and M. L. Snaith, “Thrombotic thrombocytopenic purpura occurring in a patient with mixed connective tissue disease,” Rheumatology International, vol. 4, no. 3, pp. 141–142, 1984. View at Google Scholar · View at Scopus
  14. E. J. ter Borg, P. M. Houtman, C. G. Kallenberg, M. A. Van Leeuwen, and M. H. Van Rijswijk, “Thrombocytopenia and hemolytic anemia in a patient with mixed connective tissue disease due to thrombotic thrombocytopenic purpura,” Journal of Rheumatology, vol. 15, no. 7, pp. 1174–1177, 1988. View at Google Scholar · View at Scopus
  15. P. Poullin, P. Lefevre, and J. M. Durand, “Mixed connective tissue disease with hemolytic anemia and severe thrombocytopenia due to thrombotic thrombocytopenic purpura,” American Journal of Hematology, vol. 61, no. 4, article 275, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. B. W. Baron, M. S. Martin, B. S. Sucharetza, H. R. Jeon, and J. M. Baron, “Four patients with both thrombotic thrombocytopenic purpura and autoimmune thrombocytopenic purpura: the concept of a mixed immune thrombocytopenia syndrome and indications for plasma exchange,” Journal of Clinical Apheresis, vol. 16, no. 4, pp. 179–185, 2001. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Kato, Y. Suzuki, Y. Fujigaki et al., “Thrombotic thrombocytopenic purpura associated with mixed connective tissue disease,” Rheumatology International, vol. 22, no. 3, pp. 122–125, 2002. View at Google Scholar
  18. S. Jayabose, O. Levendoglu-Tugal, M. F. Ozkayanak, C. P. Chao, B. Cuccovia, and C. Sandoval, “Use of vincristine and cyclosporine in childhood thrombotic thrombocytopenic purpura,” Journal of Pediatric Hematology/Oncology, vol. 25, no. 5, pp. 421–425, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Kuroda, K. Matsuyama, T. Nakatsue et al., “A case of mixed connective tissue disease complicated with thrombotic thrombocytopenic purpura,” Clinical Rheumatology, vol. 26, no. 1, pp. 101–104, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Gupta, H. Roppelt, B. Bowers, D. Kunz, M. Natarajan, and B. Gruber, “Successful remission of thrombotic thrombocytopenic purpura with rituximab in a patient with undifferentiated connective tissue disorder,” Journal of Clinical Rheumatology, vol. 14, no. 2, pp. 94–96, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. N. Kajita, Y. Muro, A. Tomita et al., “Thrombotic thrombocytopenic purpura with mixed connective tissue disease. A case report,” Japanese Journal of Allergology, vol. 58, no. 5, pp. 567–572, 2009. View at Google Scholar · View at Scopus
  22. M. Santiago and B. Leitão, “Prevention of strongyloides hyperinfection syndrome: a rheumatological point of view,” European Journal of Internal Medicine, vol. 20, no. 8, pp. 744–748, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Furlan, R. Robles, M. Galbusera et al., “Von willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome,” The New England Journal of Medicine, vol. 339, no. 22, pp. 1578–1584, 1998. View at Publisher · View at Google Scholar · View at Scopus
  24. H. M. Tsai and E. C. Y. Lian, “Antibodies to von willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura,” The New England Journal of Medicine, vol. 339, no. 22, pp. 1585–1594, 1998. View at Publisher · View at Google Scholar · View at Scopus
  25. J. A. Hovinga, S. K. Vesely, D. R. Terrell, B. Lammle, and J. N. George, “Survival and relapse in patients with thrombotic thrombocytopenic purpura,” Blood, vol. 115, no. 8, pp. 1500–1511, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. J. N. George, “How I treat patients with thrombotic thrombocytopenic purpura,” Blood, vol. 116, no. 20, pp. 4060–4069, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. E. Bodolay, F. Bojan, G. Szegedi, V. Stenszky, and N. R. Farid, “Cytotoxic endothelial cell antibodies in mixed connective tissue disease,” Immunology Letters, vol. 20, no. 2, pp. 163–168, 1989. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Munkvad, J. Gram, and J. Jespersen, “Depressed plasma fibrinolytic activity in a group of patients with connective tissue diseases,” Scandinavian Journal of Rheumatology, vol. 18, no. 5, pp. 277–282, 1989. View at Google Scholar · View at Scopus
  29. A. M. Manadan, C. Harris, and J. A. Block, “Thrombotic thrombocytopenic purpura in the setting of systemic sclerosis,” Seminars in Arthritis and Rheumatism, vol. 34, no. 4, pp. 683–688, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. I. Batal, R. T. Domsic, T. A. Medsger, and S. Bastacky, “Scleroderma renal crisis: a pathology perspective,” International Journal of Rheumatology, vol. 2010, Article ID 543704, 7 pages, 2010. View at Publisher · View at Google Scholar
  31. G. A. Rock, K. H. Shumak, N. A. Buskard et al., “Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian apheresis study group,” The New England Journal of Medicine, vol. 325, no. 6, pp. 393–397, 1991. View at Google Scholar
  32. N. Novitzky, J. Thomson, L. Abrahams, C. Du Toit, and A. McDonald, “Thrombotic thrombocytopenic purpura in patients with retroviral infection is hiqhly responsive to plasma infusion therapy,” British Journal of Haematology, vol. 128, no. 3, pp. 373–379, 2005. View at Publisher · View at Google Scholar · View at Scopus
  33. P. Coppo, A. Bussel, S. Charrier et al., “High-dose plasma infusion versus plasma exchange as early treatment of thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome,” Medicine, vol. 82, no. 1, pp. 27–38, 2003. View at Publisher · View at Google Scholar · View at Scopus